Properties
Description
Bis-PEG15-acid is a PEG linker featuring terminal carboxylic acid moieties. Its hydrophilic PEG spacer enhances the water solubility of compounds in aqueous media. The terminal carboxylic acids exhibit reactivity, enabling the formation of stable amide bonds when paired with primary amine groups in the presence of activators such as EDC or HATU.
Molecular Formula
C34H66O19
Functional Group 1
Carboxylic acid
Form
Liquid/Solid (low melting point)
Identity
Confirmed by NMR.
Applications
Bis-PEG15-acid is widely used in bioconjugation and drug delivery applications. It serves as a versatile tool for functionalizing biomolecules and constructing conjugates with enhanced aqueous solubility. By facilitating the formation of stable amide bonds, it enables the development of bioactive compounds and pharmaceutical formulations with improved stability and biocompatibility.