Carboxylic acid PEG reagent, Bis-PEG6-acid, Purity 98%

Synonym: 119189-70-7; Bis-PEG6-acid; COOH-PEG5-COOH; 4,7,10,13,16,19-Hexaoxadocosanedioic acid; HOOCCH₂CH₂O-PEG5-CH₂CH₂COOH

CAS Number: 119189-70-7
PubChem CID: 60146159

Size

100 mg; 250 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bis-PEG6-acid is a PEG linker featuring two terminal carboxylic acid groups. Its hydrophilic PEG spacer enhances solubility in aqueous media. The terminal carboxylic acids are capable of forming stable amide bonds with primary amine groups in the presence of activators such as EDC or HATU.

Molecular Weight

382.4

Molecular Formula

C₁₆H₃₀O₁₀

Functional Group 1

Carboxylic acid

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Amine

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Bis-PEG6-acid finds applications in bioconjugation, chemical modification, and surface functionalization. It is widely utilized in the synthesis of biomolecule conjugates, including peptides, proteins, and nucleic acids, enabling the attachment of various ligands or payloads. Moreover, it is employed in the development of drug delivery systems, diagnostic tools, and biomedical devices due to its ability to modify surfaces and enhance biocompatibility.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.