Carboxylic acid PEG reagent, Bis-PEG7-acid, Purity 98%

Synonym: 94376-75-7; Bis-PEG7-acid; Bis(3-PEG6)propionic acid; 4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid; 4,7,10,13,16,19,22-HEPTAOXAPENTACOSANE-1,25-DIOIC ACID

CAS Number: 94376-75-7
PubChem CID: 18374605

Size

250 mg; 1 g; 5 g; 10 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bis-PEG7-acid is a PEG linker featuring two terminal carboxylic acid groups. Its hydrophilic PEG spacer enhances solubility in aqueous media. The terminal carboxylic acids facilitate the formation of stable amide bonds with primary amine groups in the presence of activators like EDC or HATU.

Molecular Weight

426.5

Molecular Formula

C₁₈H₃₄O₁₁

Functional Group 1

Carboxylic acid

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Amine

Form

Colorless liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Bis-PEG7-acid finds utility in various bioconjugation and crosslinking applications. It serves as a versatile linker for attaching biomolecules to surfaces, nanoparticles, or other carriers via- amide bond formation. Additionally, it can be employed in the synthesis of multifunctional macromolecules and drug delivery systems, where precise control over linker length and functionality is crucial for optimizing bioactivity and pharmacokinetics.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.