Carboxylic acid PEG reagent, Fmoc-Lys(biotin-PEG12)-OH, Purity 98%

Synonym: BP-22614; 6-[3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-Hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid

PubChem CID: 91757813

Size

100 mg; 250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Fmoc-Lys (biotin-PEG12)-OH is a biotinylation reagent featuring lysine embedding and a carboxylic group. The carboxylic group facilitates stable and irreversible amide bond formation with primary amines (-NH2) upon reaction. Additionally, the Fmoc protecting group can be easily removed under basic conditions, yielding a free amine suitable for subsequent conjugation reactions. The hydrophilic PEG spacer arm contributes to water solubility, enhancing the solubility of the resulting biotinylated molecule.

Molecular Weight

1,194.5

Molecular Formula

C₅₈H₉₁N₅O₁₉S

Functional Group 1

Carboxylic acid

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Amine

Form

Reported

Purity

98%

Identity

Confirmed by NMR.

Applications

Fmoc-Lys (biotin-PEG12)-OH is well-suited for the site-specific biotinylation of proteins, peptides, and other biomolecules containing primary amine groups. The reaction between the carboxylic group and primary amines forms stable amide bonds, enabling precise and irreversible conjugation. After deprotection of the Fmoc group, the resulting free amine can be utilized for further modifications or conjugations.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.