Cat. No.: X24-12-LY0016
Carboxylic acid/tert-Butoxycarbonyl PEG reagent, t-Boc-N-amido-PEG-CH2COOH, MW 10,000, Purity≥95%
Synonym: Carboxylic acid/tert-Butoxycarbonyl PEG reagent; t-Boc-N-amido-PEG-CH2COOH
Properties
Description
t-Boc-N-amido-PEG-CH2COOH is an amine protected polydisperse PEG. The carboxylic acid is reactive with amine in the presence of activating agent, such as EDC or HATU. The tert-butoxycarbon-based protecting group (t-boc) can be easily removed under acidic conditions to produce a free amine, which is then reacted with NHS.
Molecular Weight
10,000 Da
Functional Group 1
Carboxylic acid
Functional Group 2
tert-Butoxycarbonyl
Identity
Confirmed by NMR.
Applications
t-Boc-N-amido-PEG-CH2COOH can be used to protect amino groups in amino acids or peptides to facilitate selective reactions in biosynthesis.
For Research Use Only. Not For
Clinical Use.