Carboxylic acid/NHS PEG reagent, Acid-PEG13-NHS ester, Purity 95%

Synonym: 1643594-31-3; Acid-PEG13-NHS ester; COOH-PEG13-NHS; 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

CAS Number: 1643594-31-3
PubChem CID: 86276394

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Acid-PEG13-NHS ester functions as a PEG linker featuring both a carboxylic acid and an NHS ester moiety. Its hydrophilic PEG spacer improves solubility in water-based environments. The terminal carboxylic acid can react with primary amines when activated by agents such as EDC or HATU to form stable amide bonds. Additionally, the NHS ester allows for labeling of primary amines t-within proteins or other similar molecules containing amino functionalities.

Molecular Weight

787.9

Molecular Formula

C₃₄H₆₁NO₁₉

Functional Group 1

Acid

Functional Group 2

Ester

Functional Group 3

NHS

Reactive Group 1

Amine

Form

Solid or viscous liquid

Purity

95%

Identity

Confirmed by NMR.

Applications

This compound is utilized in bioconjugation for the attachment of biomolecules, such as proteins or peptides, to surfaces or other macromolecules. The NHS (N-hydroxysuccinimide) group facilitates the formation of stable amide bonds with primary amines, making it suitable for drug delivery and development of conjugated therapeutics.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.