Description
PCL(3k)-PEG(1k)-COOH is a linear biodegradable amphiphilic polymer consists of a polycaprolactone (PCL) block and a hydrophilic shell (PEG) block. The carboxylic acid reacts with primary amines in the presence of an activator (e.g., HATU/EDC) to form an amide bond.
Applications
PCL(3k)-PEG(1k)-COOH can be used to prepare nanoparticles or functional coatings to improve the solubility of materials, reduce immunogenicity, and enhance their stability in specific environments.