Cereblon/IBT6A PEG reagent, P131, Purity 95%

Synonym: CHEMBL4450122; SCHEMBL22738045; PD142783

CAS Number: 2360561-66-4
PubChem CID: 155358332

Size

50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

P131 is a reagent grade PROTAC molecule comprised of Pomalidomide-based cereblon ligand and IBT6A, linked by a PEG 3 chain.

Molecular Weight

913

Molecular Formula

C₄₆H₄₈N₁₂O₉

Functional Group 1

Cereblon

Functional Group 2

IBT6A

Functional Group 3

None

Form

Solid

Purity

95%

Identity

Confirmed by NMR.

Applications

P131 is a PROTAC molecule comprised which was initially developed by Sun (2018) that can degrade both wild-type and C481S mutant BTK with nanomolar potencies.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.