Chloroacetamido PEG reagent, Bromo-PEG12-t-butyl ester, Purity 95%

Synonym: BP-24439; HY-132117; CS-0148584

PubChem CID: 129012176

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromo-PEG12-t-butyl ester is a PEG linker featuring a bromide group and a t-butyl protected carboxyl group. The inclusion of a hydrophilic PEG spacer enhances solubility in aqueous media. The bromide (Br) serves as an efficient leaving group for facilitating nucleophilic substitution reactions. The t-butyl protected carboxyl group can undergo deprotection under acidic conditions.

Molecular Weight

373.7

Molecular Formula

C₃₁H₆₁BrO₁₄

Functional Group 1

Chloroacetamido

Functional Group 2

None

Functional Group 3

None

Form

Liquid

Purity

95%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Bromo-PEG12-t-butyl ester is utilized in bioconjugation strategies, particularly in the modification of biomolecules for various biomedical applications. It enables the covalent attachment of proteins, peptides, or other molecules to surfaces or carriers via- nucleophilic substitution reactions. Additionally, it serves as a versatile tool in the synthesis of functionalized PEG-based materials, such as hydrogels or nanoparticles, for drug delivery and tissue engineering applications.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.