Chloroacetamido PEG reagent, Bromo-PEG5-t-butyl ester, Purity 98%

Synonym: 1415800-38-2; Bromo-PEG5-t-butyl ester; Bromo-PEG5-Boc; Bromo-PEG5-t-butylester; Br-PEG5-COOtBu

CAS Number: 1415800-38-2
PubChem CID: 77078502

Size

250 mg; 500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromo-PEG5-t-butyl ester is a PEG linker comprising a bromide group and a t-butyl protected carboxyl group. Its hydrophilic PEG spacer enhances solubility in aqueous media. The bromide (Br) serves as an efficient leaving group for facilitating nucleophilic substitution reactions. The t-butyl protected carboxyl group can be selectively removed under acidic conditions.

Molecular Weight

429.4

Molecular Formula

C₁₇H₃₃BrO₇

Functional Group 1

Chloroacetamido

Functional Group 2

None

Functional Group 3

None

Form

Liquid

Purity

98%

Solubility

DMSO, DCM,DMF

Identity

Confirmed by NMR.

Applications

Bromo-PEG5-t-butyl ester is widely utilized in bioconjugation and chemical synthesis applications. Its compatibility with aqueous environments makes it suitable for conjugation reactions in biological settings. This linker is commonly employed in the modification of biomolecules, surface functionalization, and the development of bioactive compounds and materials.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.