Chloroacetamido PEG reagent, Bromo-PEG8-t-butyl ester, Purity 98%

Synonym: 1623792-00-6; Bromo-PEG8-t-butyl ester; Bromo-PEG8-Boc; Br-PEG8-COOtBu; Bromo-PEG8-t-butylester

CAS Number: 1623792-00-6
PubChem CID: 77078295

Size

100 mg; 250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromo-PEG8-t-butyl ester is a PEG linker equipped with a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer enhances solubility in aqueous environments. The bromide serves as an effective leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can undergo deprotection under acidic conditions.

Molecular Weight

561.5

Molecular Formula

C₂₃H₄₅BrO₁₀

Functional Group 1

Chloroacetamido

Functional Group 2

None

Functional Group 3

None

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Bromo-PEG8-t-butyl ester finds application in bioconjugation chemistry for linking biomolecules to surfaces or other molecules via- nucleophilic substitution reactions. Additionally, it is employed in the synthesis of functionalized PEG-based materials for various biomedical applications, including drug delivery systems and diagnostic tools.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.