Chloroacetamido PEG reagent, Chloroacetamido-PEG4-t-butyl ester, Purity 98%

Synonym: 1365655-90-8; Chloroacetamido-PEG4-t-butyl ester; Chloroacetamido-PEG4-C2-Boc; Tert-Butyl 1-chloro-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate; Chloroacetamido-PEG5-t-butyl ester

CAS Number: 1365655-90-8
PubChem CID: 60146192

Size

250 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Chloroacetamido-PEG4-t-butyl ester features a chloroacetamide and a t-butyl ester. The chlorine acts as a proficient leaving group in substitution reactions. The t-butyl group serves as an acid labile protective group, allowing for subsequent chemical modification. The hydrophilic PEG chain enhances water solubility in aqueous environments.

Molecular Weight

397.9

Molecular Formula

C₁₇H₃₂ClNO₇

Functional Group 1

Chloroacetamido

Functional Group 2

None

Functional Group 3

None

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Chloroacetamido-PEG4-t-butyl ester is utilized in diverse chemical synthesis and bioconjugation applications. Its chlorine moiety facilitates nucleophilic substitution reactions, while the t-butyl ester offers protection during synthesis. This linker is commonly employed in the modification of biomolecules, surface functionalization, and the synthesis of pharmaceutical compounds and materials.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.