Chloroacetamido/NHS PEG reagent, Chloroacetamido-PEG4-NHS ester, Purity 98%

Synonym: 1353011-95-6; CHLOROACETAMIDO-PEG4-NHS ESTER; Cl-peg4-nhsester; Cl-PEG4-NHS ester; 2,5-Dioxopyrrolidin-1-yl 1-chloro-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate

CAS Number: 1353011-95-6
PubChem CID: 60146178

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Chloroacetamido-PEG4-NHS ester is a PEG linker equipped with chloroacetamide and NHS ester functionalities. The chlorine serves as a proficient leaving group, facilitating substitution reactions. Meanwhile, the NHS ester acts as an active ester, facilitating the formation of stable amide bonds with primary amines. Its hydrophilic PEG linker enhances the compound's hydrophilicity in aqueous environments.

Molecular Weight

438.9

Molecular Formula

C₁₇H₂₇ClN₂O₉

Functional Group 1

Chloroacetamido

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Amine

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Chloroacetamido-PEG4-NHS ester is extensively utilized in bioconjugation and chemical modification applications. Its chloroacetamide moiety enables efficient conjugation with various nucleophiles, while the NHS ester group facilitates selective coupling with primary amines of biomolecules.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.