DBCO PEG reagent, 4-Arm PEG5-DBCO, Purity 95%

Synonym: 4-Arm PEG5-DBCO; BP-29735

PubChem CID: 167312733

Size

25 mg; 50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

4-Arm PEG5-DBCO is a versatile 4-arm branched PEG linker featuring four DBCO (Dibenzocyclooctyne) moieties. DBCO is widely utilized in copper-free Click Chemistry reactions due to its high reactivity with azides. The presence of the hydrophilic PEG spacer in this compound enhances its water solubility, facilitating its application in aqueous environments for bioconjugation and drug delivery purposes.

Molecular Weight

2,162.6

Molecular Formula

C₁₂₁H₁₄₈N₈O₂₈

Functional Group 1

DBCO

Functional Group 2

None

Functional Group 3

None

Form

Reported

Purity

95%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

4-Arm PEG5-DBCO can be used in bioconjugation and drug delivery applications. The DBCO groups enable efficient conjugation with azide-containing molecules through copper-free Click Chemistry, facilitating the construction of diverse biomolecular assemblies, such as protein-polymer conjugates and nanoparticle formulations. The branched structure of 4-Arm PEG5-DBCO offers increased connectivity and versatility, allowing for the simultaneous modification of multiple functional groups within complex molecular architectures, thereby enabling the development of advanced biomaterials and therapeutics with tailored properties and functionalities.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.