Description
DBCO-C3-PEG4-NH-Boc is a copper-free click chemistry compound designed for versatile bioconjugation applications. Featuring a DBCO functional group, it readily participates in copper-free Click Chemistry reactions with azides, facilitating the efficient and bioorthogonal labeling of biomolecules. Additionally, the presence of a Boc protecting group ensures the stability of the amine functionality during synthesis and storage, which can be selectively removed under mild acidic conditions to reveal the free amine for further functionalization.
Applications
DBCO-C3-PEG4-NH-Boc can be used as a valuable tool for the precise and selective modification of biomolecules without the need for harsh reaction conditions or potentially cytotoxic copper catalysts. Its compatibility with copper-free Click Chemistry reactions allows for the labeling of biomolecules in complex biological environments, including live cells and tissues. Furthermore, the presence of the Boc protecting group offers flexibility in the synthesis process, enabling the controlled introduction of functional groups while ensuring the stability of the amine moiety.