DBCO PEG reagent, DNP-PEG4-DBCO, Purity 98%

Synonym: 2149585-17-9; DNP-PEG4-DBCO; AKOS040743238; BP-24022; HY-140619

CAS Number: 2149585-17-9
PubChem CID: 134159734

Size

50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DNP-PEG4-DBCO is a bifunctional PEG linker featuring a dinitrophenyl (DNP) moiety and a dibenzocyclooctyne (DBCO) moiety. DNP is renowned for its role in biological applications, including ion transport across membranes, while DBCO facilitates copper-free Click Chemistry reactions owing to its strain-promoted high-energy cycloaddition with azides. The polyethylene glycol (PEG) spacer provides flexibility and solubility, making it suitable for various bioconjugation applications.

Molecular Weight

689.7

Molecular Formula

C₃₅H₃₉N₅O₁₀

Functional Group 1

DBCO

Functional Group 2

None

Functional Group 3

None

Form

Semi-Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

DNP-PEG4-DBCO can be used in bioconjugation and biomolecule labeling studies, especially in the development of bioorthogonal systems for selective and efficient conjugation. The DNP moiety enables specific interactions with target biomolecules or cellular components, making it valuable for applications such as protein labeling, drug delivery, and molecular imaging. Meanwhile, the DBCO group offers rapid and bioorthogonal conjugation with azide-containing molecules, facilitating the construction of complex biomolecular architectures with minimal background interference.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.