DBCO/Desthiobiotin PEG reagent, DBCO-PEG4-Desthiobiotin, Purity 98%

Synonym: 2032788-37-5; DBCO-PEG4-desthiobiotin; AKOS040743203; BP-22451; HY-140301

CAS Number: 2032788-37-5
PubChem CID: 86580455

Size

10 mg; 25 mg; 100 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-PEG4-desthiobiotin is a reagent grade single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin.

Molecular Weight

719.9

Molecular Formula

C₃₉H₅₃N₅O₈

Functional Group 1

DBCO

Functional Group 2

Desthiobiotin

Functional Group 3

None

Reactive Group 1

Azide

Form

Solid (low melting point)

Purity

98%

Identity

Confirmed by NMR.

Applications

DBCO-PEG4-desthiobiotin is used in bioconjugation and molecular biology research, enabling efficient copper-free Click Chemistry reactions. It is ideal for pull-down experiments with biological samples, allowing for specific elution from streptavidin affinity resin using mild conditions, and minimizing co-purification of endogenous biotinylated molecules.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.