Cat. No.: X24-03-YW0315
DBCO/Hydroxy PEG reagent, DBCO-sulfo-NHS ester, Purity 90%
Synonym: 1400191-52-7; DBCO-sulfo-NHS ester; DBCO-Sulfo-NHS ester sodium; DBCO-Sulfo-NHS ester (sodium); 1-[6-(2-Azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-6-oxohexanoyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
- CAS Number: 1400191-52-7
- PubChem CID: 77078153
Size
25 mg; 100 mg; 250 mg; 500 mg
Properties
Description
DBCO-Sulfo-NHS ester is a water-soluble sulfonated reagent featuring a DBCO moiety, designed for simple and efficient labeling of antibodies, proteins, and other primary amine-bearing macromolecules. With its sulfo modification, this reagent offers enhanced solubility and stability in aqueous buffers, making it suitable for a wide range of bioconjugation applications. The DBCO moiety enables specific and rapid bioorthogonal conjugation via- copper-free Click Chemistry reactions, facilitating the creation of stable and site-specific biomolecule conjugates.
Molecular Formula
C25H21N2NaO8S
Functional Group 2
Hydroxy
Identity
Confirmed by NMR.
Applications
DBCO-Sulfo-NHS ester is widely utilized in research settings for the selective labeling and modification of biomolecules with DBCO functionalities under mild aqueous conditions. Its water solubility and compatibility with biological systems make it ideal for applications such as protein labeling, antibody conjugation, and biomolecule imaging. By enabling the formation of covalent bonds between DBCO-labeled molecules and azide-bearing compounds without the need for copper catalysts, DBCO-Sulfo-NHS ester offers a versatile tool for bioconjugation studies and the development of novel bioanalytical techniques.
For Research Use Only. Not For
Clinical Use.
