DBCO/Maleimide PEG reagent, DBCO-PEG12-Maleimide, Purity 95%

Synonym: 2011777-01-6; DBCO-NHCO-PEG12-maleimide; DBCO-PEG(12)-MAL; DBCO-NH-PEG12-Maleimide; DBCO-PEG12-Maleimide

CAS Number: 2011777-01-6
PubChem CID: 118988590

Size

25 mg; 50 mg; 100 mg; 250 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-PEG12-Maleimide is a reagent grade PEG linker featuring a DBCO moiety and a terminal primary maleimide group, designed for copper-free Click Chemistry reactions. The maleimide group reacts with thiol groups to form covalent bonds.

Molecular Weight

1,027.2

Molecular Formula

C₅₂H₇₄N₄O₁₇

Functional Group 1

DBCO

Functional Group 2

Maleimide

Functional Group 3

None

Reactive Group 1

Azide

Reactive Group 2

Thiol

Form

Solid/liquid (low melting point)

Purity

95%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

DBCO-PEG12-Maleimide is used in bioconjugation and molecular biology research, facilitating efficient copper-free Click Chemistry reactions. Its maleimide group allows for the connection of biomolecules with thiol groups, making it ideal for studying protein interactions and developing targeted drug delivery systems.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.