DBCO/Maleimide PEG reagent, DBCO-PEG24-Maleimide, Purity 95%

Synonym: DBCO-PEG24-Maleimide; DBCO-PEG24-MAL; GS-9440; BP-25731; G76933

PubChem CID: 155906774

Size

25 mg; 50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-PEG24-Maleimide is a versatile PEG linker featuring a DBCO moiety and a terminal primary maleimide group. The maleimide group serves as a reactive handle for the specific conjugation of thiol-containing biomolecules, allowing for the formation of stable covalent bonds. With a long PEG spacer arm consisting of 24 ethylene glycol units, this linker provides flexibility and hydrophilicity, facilitating efficient biomolecule labeling and conjugation in aqueous environments.

Molecular Weight

1,555.8

Molecular Formula

C₇₆H₁₂₂N₄O₂₉

Functional Group 1

DBCO

Functional Group 2

Maleimide

Functional Group 3

None

Reactive Group 1

Thiol

Form

Oil

Purity

95%

Identity

Confirmed by NMR.

Applications

DBCO-PEG24-Maleimide can be used in bioconjugation and biomolecule modification applications where selective and stable linkage between thiol-containing molecules is desired. The maleimide group readily reacts with thiols under mild conditions, enabling the site-specific labeling of proteins, peptides, antibodies, and other biomolecules. Additionally, the extended PEG spacer arm enhances the solubility and biocompatibility of the conjugates.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.