DBCO/Maleimide PEG reagent, DBCO-PEG4-Maleimide, Purity 95%

Synonym: 1480516-75-3; DBCO-PEG4-Maleimide; Dibenzocyclooctyne-PEG4 maleimide; DBCO-PEG4-MAL; DBCO-NH-PEG4-Maleimide

CAS Number: 1480516-75-3
PubChem CID: 86580488

Size

10 mg; 25 mg; 100 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-PEG4-Maleimide is a reagent grade PEG linker containing a maleimide group and a DBCO moiety. The hydrophilic PEG spacer arm improves solubility in aqueous buffers.

Molecular Weight

674.8

Molecular Formula

C₃₆H₄₂N₄O₉

Functional Group 1

DBCO

Functional Group 2

Maleimide

Functional Group 3

None

Reactive Group 1

Azide

Reactive Group 2

Thiol

Form

Sticky liquid

Purity

95%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

DBCO-PEG4-Maleimide is used in bioconjugation and molecular biology research, enabling efficient copper-free Click Chemistry reactions. Its maleimide group reacts specifically and efficiently with thiols to form stable thioether bonds, ideal for modifying cysteine-containing peptides.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.