DBCO/NHS PEG reagent, DBCO-C6-NHS ester, Purity 98%

Synonym: 1384870-47-6; DBCO-C6-NHS ester; DBCO-NHS ester 2; DBCO NHS ester; DBCO-C6-NHSester

CAS Number: 1384870-47-6
PubChem CID: 86580459

Size

100 mg; 250 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-C6-NHS ester is an amine-reactive compound designed for the modification of amine-containing molecules in organic media. This reagent exhibits limited solubility in aqueous environments but demonstrates enhanced solubility in various organic solvents commonly used in bioconjugation chemistry, including dichloromethane, chloroform, THF, and ethyl acetate. Featuring an extended 6-carbon atom spacer arm, DBCO-C6-NHS ester offers improved solubility and efficiency in derivatization reactions, leading to the formation of stable conjugates with enhanced stability.

Molecular Weight

430.5

Molecular Formula

C₂₅H₂₂N₂O₅

Functional Group 1

DBCO

Functional Group 2

NHS

Functional Group 3

None

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

DBCO-C6-NHS ester is particularly useful for modifying biomolecules with amine functionalities in organic solvents, enabling the synthesis of bioconjugates under conditions where aqueous solubility is not required. DBCO-C6-NHS ester can be employed in various bioconjugation strategies, including the labeling of proteins, peptides, and nucleic acids with DBCO-functionalized molecules. Its extended spacer arm enhances the stability and efficiency of conjugation reactions.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.