DBCO/NHS PEG reagent, DBCO-NHS, Purity 97%

Synonym: 1353016-71-3; DBCO-NHS; Dbco-nhs ester; MFCD24386367; Dibenzocyclooctyne-N-hydroxysuccinimidyl ester

MDL: MFCD24386367
CAS Number: 1353016-71-3
PubChem CID: 77078178

Size

50 mg; 100 mg; 250 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-NHS ester is a reagent grade amine-reactive click chemistry reagent that modifies amine-containing molecules in organic solvents. It reacts with primary amines, such as lysine side chains or aminosilane-coated surfaces, at neutral or slightly basic pH to form covalent bonds.

Molecular Weight

402.4

Molecular Formula

C₂₃H₁₈N₂O₅

Functional Group 1

DBCO

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Amine

Reactive Group 2

Azide

Form

Solid

Purity

97%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

DBCO-NHS ester is used in bioconjugation and molecular biology research for modifying amine-containing molecules through copper-free Click Chemistry reactions. Its low mass weight ensures minimal spacer addition, making it ideal for studies involving protein interactions and surface modifications.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.