Description
DBCO-PEG2-NHS ester is a reagent grade click chemistry PEG reagent containing an NHS ester that reacts specifically and efficiently with primary amines at neutral or slightly basic conditions to form a covalent bond. The hydrophilic PEG spacer arm enhances water solubility and provides a long, flexible connection that minimizes steric hindrance during ligation.
Applications
DBCO-PEG2-NHS ester is used in bioconjugation and molecular biology research, enabling efficient copper-free Click Chemistry reactions with azides. Its NHS ester allows for the specific modification of primary amines, making it ideal for studying protein interactions and enhancing surface modifications.