Description
DBCO-PEG24-NHS ester is a reagent grade click chemistry PEG reagent containing an NHS ester that specifically and efficiently reacts with primary amines at neutral or slightly basic conditions to form a covalent bond. The hydrophilic PEG spacer arm enhances water solubility and provides a long, flexible connection that minimizes steric hindrance during ligation.
Applications
DBCO-PEG24-NHS ester is used in bioconjugation and molecular biology research, facilitating efficient copper-free Click Chemistry reactions. Its NHS ester enables specific modification of primary amines, making it ideal for studying protein interactions and enhancing surface modifications with improved water solubility and reduced steric hindrance.