DBCO/NHS PEG reagent, DBCO-PEG4-NHS ester, Purity 98%

Synonym: 1427004-19-0; DBCO-PEG4-NHS ester; DBCO-PEG4-SPA

CAS Number: 1427004-19-0
PubChem CID: 77078155

Size

25 mg; 100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-PEG4-NHS Ester is a reagent grade click chemistry PEG reagent containing an NHS ester that reacts specifically and efficiently with primary amines at neutral or slightly basic conditions to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long, flexible connection that minimizes steric hindrance.

Molecular Weight

649.7

Molecular Formula

C₃₄H₃₉N₃O₁₀

Functional Group 1

DBCO

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Amine

Reactive Group 2

Azide

Form

Sticky gel

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

DBCO-PEG4-NHS Ester is used in bioconjugation and molecular biology research, enabling efficient copper-free Click Chemistry reactions. Its NHS ester allows for specific modification of primary amines, making it ideal for studying protein interactions and enhancing surface modifications with improved solubility and reduced steric hindrance.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.