Cat. No.: X24-03-YW0329
Diketone/DBCO PEG reagent, Diketone-PEG12-DBCO, Purity 98%
Synonym: Diketone-PEG12-DBCO; AKOS040743229; BP-24347; HY-140450; CS-0115415
Properties
Description
Diketone-PEG12-DBCO belongs to a category of PEG linkers characterized by the presence of a diketone group and a DBCO (dibenzocyclooctyne) group. These linkers are designed for bioconjugation applications, where the DBCO group facilitates copper-free Click Chemistry reactions with azide-bearing compounds or biomolecules. The resulting triazole linkage formed between the diketone-PEG12-DBCO linker and the azide-containing moiety is stable and suitable for various biomedical and biochemical applications.
Molecular Formula
C58H81N3O17
Functional Group 1
Diketone
Identity
Confirmed by NMR.
Applications
Diketone-PEG12-DBCO is widely used in bioconjugation studies and drug delivery applications. By exploiting the selective reactivity of the DBCO group towards azides, diketone-PEG12-DBCO enables the efficient and bioorthogonal labeling of biomolecules without the need for copper catalysts. This feature makes it valuable in the development of targeted therapeutics, imaging probes, and diagnostic tools.
For Research Use Only. Not For
Clinical Use.