Diketone/DBCO PEG reagent, Diketone-PEG12-DBCO, Purity 98%

Synonym: Diketone-PEG12-DBCO; AKOS040743229; BP-24347; HY-140450; CS-0115415

PubChem CID: 138455134

Size

10 mg; 25 mg; 50 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Diketone-PEG12-DBCO belongs to a category of PEG linkers characterized by the presence of a diketone group and a DBCO (dibenzocyclooctyne) group. These linkers are designed for bioconjugation applications, where the DBCO group facilitates copper-free Click Chemistry reactions with azide-bearing compounds or biomolecules. The resulting triazole linkage formed between the diketone-PEG12-DBCO linker and the azide-containing moiety is stable and suitable for various biomedical and biochemical applications.

Molecular Weight

1,092.3

Molecular Formula

C₅₈H₈₁N₃O₁₇

Functional Group 1

Diketone

Functional Group 2

DBCO

Functional Group 3

None

Reactive Group 1

Azide

Form

Oil

Purity

98%

Identity

Confirmed by NMR.

Applications

Diketone-PEG12-DBCO is widely used in bioconjugation studies and drug delivery applications. By exploiting the selective reactivity of the DBCO group towards azides, diketone-PEG12-DBCO enables the efficient and bioorthogonal labeling of biomolecules without the need for copper catalysts. This feature makes it valuable in the development of targeted therapeutics, imaging probes, and diagnostic tools.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.