Diketone/PFP PEG reagent, Diketone-PEG11-PFP ester, Purity 97%

Synonym: 2353409-86-4; Diketone-PEG11-PFP ester; AKOS040743227; BP-24184; HY-140447; CS-0115413

CAS Number: 2353409-86-4
PubChem CID: 137334063

Size

25 mg; 50 mg; 100 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Diketone-PEG11-PFP ester is a PEG linker featuring a diketone group and a PFP (pentafluorophenyl) ester group. The PFP ester is an activated ester known for its reactivity with primary amines, leading to the formation of stable amide bonds. Notably, the PFP ester exhibits enhanced stability compared to other amine-reactive groups, as it is less susceptible to hydrolysis. This stability ensures efficient and reliable conjugation reactions with primary amine-containing molecules.

Molecular Weight

956.0

Molecular Formula

C₄₄H₆₂F₅NO₁₆

Functional Group 1

Diketone

Functional Group 2

PFP

Functional Group 3

None

Reactive Group 1

Azide

Form

Oil

Purity

97%

Identity

Confirmed by NMR.

Applications

Diketone-PEG11-PFP ester can be used in bioconjugation applications, particularly for the modification of biomolecules with primary amine functionalities. Through its reaction with primary amines, the PFP ester enables the conjugation of the diketone-PEG11 linker to proteins, peptides, antibodies, and other amine-containing molecules, facilitating the development of bioconjugates for various biomedical and biotechnological purposes.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.