Diketone/PFP PEG reagent, Diketone-PEG4-PFP ester, Purity 98%

Synonym: 2353409-84-2; Diketone-PEG4-PFP ester; 2353409-84-2; Perfluorophenyl 16-((4-(3,5-dioxohexyl)phenyl)amino)-16-oxo-4,7,10,13-tetraoxahexadecanoate; AKOS040743231; BP-24186

CAS Number: 2353409-84-2
PubChem CID: 137334061

Size

25 mg; 50 mg; 100 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Diketone-PEG4-PFP ester is a PEG linker featuring a diketone group and a PFP (pentafluorophenyl) ester group. The PFP ester serves as an activated ester, facilitating the formation of amide bonds with primary amines. Recognized for its stability, the PFP ester exhibits reduced susceptibility to hydrolysis compared to other amine-reactive groups, ensuring reliable and robust bioconjugation reactions.

Molecular Weight

647.6

Molecular Formula

C₃₀H₃₄F₅NO₉

Functional Group 1

Diketone

Functional Group 2

PFP

Functional Group 3

None

Reactive Group 1

Amine

Form

Oil

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Diketone-PEG4-PFP ester can be used in bioconjugation chemistry, particularly in the modification of biomolecules containing primary amine functionalities. By reacting with primary amines, the PFP ester enables the conjugation of Diketone-PEG4-PFP ester to proteins, peptides, antibodies, and other amine-containing molecules.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.