Description
DNP-PEG12-NHS ester is a PEG linker comprising a dinitrophenyl (DNP) moiety and an NHS ester terminal group. DNP plays a role in various biological processes, including ion transport across membranes. The NHS ester functionality facilitates the conjugation of the compound to primary amines, forming stable amide bonds. Furthermore, the hydrophilic PEG linkers enhance the water solubility of the compound, making it suitable for aqueous-based applications.
Applications
DNP-PEG12-NHS ester can be widely used in bioconjugation and labeling applications. The NHS ester group enables selective modification of primary amine-containing molecules, such as proteins, peptides, and antibodies, through amide bond formation. By conjugating the DNP moiety to biomolecules of interest, researchers can facilitate detection, imaging, or tracking of specific targets in biological systems. The hydrophilic PEG linkers contribute to the compound's stability and solubility, ensuring efficient conjugation and subsequent biological activity in aqueous environments.