DOTA/t-Butyl ester PEG reagent, DOTA(OtBu)₃, Purity 95%

Synonym: 137076-54-1; Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate; 2-(4,7,10-Tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; DOTA-tri(t-butyl ester); MFCD02259697

MDL: MFCD02259697
CAS Number: 137076-54-1
PubChem CID: 11606627

Size

50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DOTA(OtBu)₃ is a DOTA derivative featuring three t-butyl ester-protected carboxyl groups, enhancing stability during synthesis. The DOTA core acts as an efficient chelator for di- and trivalent metal ions, while the t-butyl esters can be selectively removed under acidic conditions.

Molecular Weight

572.7

Molecular Formula

C₂₈H₅₂N₄O₈

Functional Group 1

DOTA

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Chelation

Form

Solid

Purity

95%

Identity

Confirmed by NMR.

Applications

DOTA(OtBu)₃ is ideal for radiolabeling, imaging diagnostics, and metal ion chelation, allowing controlled deprotection for site-specific conjugation in targeted drug delivery and biomedical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

DOTA/t-Butyl ester PEG reagent, DOTA(OtBu)3, Purity 95%

DOTA/t-Butyl ester PEG reagent, DOTA(OtBu)₃, Purity 95%