Doxorubicin/Iodoacetamide PEG reagent, N-(Iodoacetamido)-doxorubicin, Purity 95%

Synonym: 114390-30-6; N-(Iodoacetamido)-Doxorubicin; N-iodoacetyladriamycin

CAS Number: 114390-30-6
PubChem CID: 129737886

Size

25 mg; 50 mg; 100 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-(Iodoacetamido)-doxorubicin is a modified doxorubicin derivative featuring an iodoacetamido moiety. This reactive iodoacetamido group enables covalent conjugation with thiol and amine groups, while the doxorubicin core retains its potent anthracycline-based antineoplastic activity, commonly used in cancer research.

Molecular Weight

711.5

Molecular Formula

C₂₉H₃₀INO₁₂

Functional Group 1

Doxorubicin

Functional Group 2

Iodoacetamide

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Solid

Purity

95%

Solubility

DMSO, DMF

Identity

Confirmed by NMR.

Applications

N-(Iodoacetamido)-doxorubicin is employed in targeted drug delivery, antibody-drug conjugates (ADCs), and cancer research. Its iodoacetamido group allows for site-specific conjugation with biomolecules, enhancing targeted therapeutic applications and facilitating the development of novel chemotherapeutic agents.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.