Description
DSPE-hydrazone-mPEG2K is a reagent grade phospholipid polyPEG with a hydrazone group that self-assembles to form a lipid bilayer in an aqueous solution. Hydrazone linkages are useful for coupling drugs to targeted antibodies where the linkage is stable at neutral pH but is rapidly destroyed in the acidic environment of lysosomes of the cell.
Applications
DSPE-hydrazone-mPEG2K is designed to prepare liposomes as a drug delivery vehicle for the administration of drugs or nutrients, such as mRNA vaccines. Hydrazone linkages are useful for coupling drugs to targeted antibodies.