Cat. No.: X24-09-YYX228
Fmoc-protected Amine/NHS PEG reagent, Fmoc-PEG12-NHS ester, Purity 95%
Synonym: 2227246-92-4; 488085-18-3; Fmoc-PEG12-NHS ester; FmocNH-PEG12-NHS ester; Fmoc-N-amido-PEG12-NHS ester
- CAS Number: 2227246-92-4
- PubChem CID: 11535302
Size
250 mg; 500 mg; 1 g; 2 g
Properties
Description
Fmoc-PEG12-NHS ester functions as a PEG linker incorporating an Fmoc-protected amino group along with an NHS ester functionality. Its hydrophilic PEG spacer improves solubility when placed into aqueous media. The Fmoc protecting group can be removed under basic conditions to yield free aminogroups suitable for further conjugation reactions involving primary amines t-from proteins or modified oligonucleotides.
Molecular Formula
C46H68N2O18
Form
Solid or viscous liquid
Identity
Confirmed by NMR.
Applications
In peptide synthesis, it is used to add long PEG chains and Fmoc protection groups. The PEG moiety improves the solubility and pharmacokinetic properties of the peptides, making them more suitable for therapeutic use. It can also be used in the modification of proteins to create conjugates for drug delivery or for improving the stability and functionality of enzymes.
For Research Use Only. Not For
Clinical Use.