Fmoc-protected Amine/NHS PEG reagent, Fmoc-PEG24-NHS ester, Purity 98%

Synonym: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Fmoc-PEG24-NHS ester serves as a PEG linker incorporating an Fmoc-protected amine along with an NHS ester moiety. The hydrophilic nature of its PEG spacer improves solubility in water-based environments. The Fmoc group can be removed under basic conditions to yield free amines suitable for further conjugation reactions. Additionally, this NHS ester allows for labeling primary amines t-present within proteins or other similar compounds containing amino functionalities.

Molecular Weight

1465.7

Molecular Formula

C₇₀H₁₁₆N₂O₃₀

Functional Group 1

Ester

Functional Group 2

Fmoc

Functional Group 3

NHS

Reactive Group 1

Amine

Form

Solid or viscous liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Fmoc-PEG24-NHS ester is highly valuable in peptide and protein chemistry. It is commonly used in the synthesis of long-chain peptide conjugates, where the PEG moiety improves the pharmacokinetic properties of the peptides, such as increased solubility and prolonged half-life in the bloodstream.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.