Fmoc-protected Amine/NHS PEG reagent, Fmoc-PEG4-NHS ester, Purity 98%

Synonym: 1314378-14-7; Fmoc-PEG4-NHS ester; 2,5-dioxopyrrolidin-1-yl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate; FmocNH-PEG4-NHS ester; Fmoc-N-amido-PEG4-NHS ester

CAS Number: 1314378-14-7
PubChem CID: 60146207

Size

250 mg; 500 mg; 1 g; 5 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Fmoc-PEG4-NHS ester functions similarly as another PEG linker featuring an Fmoc-protected amino group alongside an NHS ester functionality. The hydrophilic nature of its PEG spacer increases solubility when placed into aqueous media, and like before, the Fmoc group can be deprotected under basic conditions to produce free aminogroups suitable for additional conjugations involving primary amines t-from proteins or modified oligonucleotides.

Molecular Weight

584.6

Molecular Formula

C₃₀H₃₆N₂O₁₀

Functional Group 1

Ester

Functional Group 2

Fmoc

Functional Group 3

NHS

Reactive Group 1

Amine

Form

Solid or viscous liquid

Purity

98%

Solubility

DMSO, DMF, DCM

Identity

Confirmed by NMR.

Applications

Fmoc-PEG4-NHS ester is commonly employed in the synthesis of peptides and the modification of biomolecules to incorporate PEG moieties and Fmoc protection.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.