Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-Amino-bis(PEG1-t-butyl ester), Purity 96%

Synonym: 1415800-34-8; Hydroxy-Amino-bis(PEG1-C2-Boc); Hydroxy-Amino-bis(PEG1-t-butyl ester); Hydroxy-Amino-(PEG1-t-butyl ester)₂

CAS Number: 1415800-34-8
PubChem CID: 77078533

Size

500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxy-Amino-bis(PEG1-t-butyl ester) is a branched PEG linker featuring a terminal hydroxyl group, an amino group, and two t-butyl-protected carboxyl groups. The hydroxyl group offers versatile sites for chemical modifications, while the t-butyl esters provide acid-labile protection for controlled activation of carboxylic acids. Its structure supports hydrophilicity and functionalization.

Molecular Weight

405.5

Molecular Formula

C₂₀H₃₉NO₇

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Solid

Purity

96%

Identity

Confirmed by NMR.

Applications

Hydroxy-Amino-bis(PEG1-t-butyl ester) is used in drug delivery, bioconjugation, and polymer synthesis. The hydroxyl and amino groups enable diverse functionalization, while the t-butyl esters allow precise carboxyl activation under acidic conditions, making it ideal for creating hydrophilic linkers and advanced materials in biomedical and pharmaceutical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.