Cat. No.: X24-03-YW0633
Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG10-t-butyl ester, Purity 98%
Synonym: 778596-26-2; Hydroxy-PEG10-t-butyl ester; HO-PEG10-CH2CH2COOtBu; HO-PEG10-tBu; Hydroxy-PEG10-Boc
- CAS Number: 778596-26-2
- PubChem CID: 11410687
Size
500 mg; 1 g; 2 g; 5 g
Properties
Description
Hydroxy-PEG10-t-butyl ester is a PEG linker featuring a terminal hydroxyl group and a t-butyl ester-protected carboxyl group. The PEG10 spacer provides enhanced hydrophilicity and solubility in aqueous media. The hydroxyl group offers a versatile site for further derivatization, while the t-butyl ester can be selectively deprotected under acidic conditions.
Molecular Formula
C27H54O13
Functional Group 1
Hydroxyl
Functional Group 2
t-Butyl ester
Reactive Group 2
Nucleophile
Solubility
Water, DMSO, DMF, DCM
Identity
Confirmed by NMR.
Applications
Hydroxy-PEG10-t-butyl ester is used in bioconjugation, drug delivery, and organic synthesis. The terminal hydroxyl group allows for various functional modifications, and the acid-labile t-butyl ester enables controlled release of the carboxylic acid, making it ideal for creating hydrophilic and functionalized biomolecule conjugates in pharmaceutical research.
For Research Use Only. Not For
Clinical Use.