Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG10-t-butyl ester, Purity 98%

Synonym: 778596-26-2; Hydroxy-PEG10-t-butyl ester; HO-PEG10-CH₂CH₂COOtBu; HO-PEG10-tBu; Hydroxy-PEG10-Boc

CAS Number: 778596-26-2
PubChem CID: 11410687

Size

500 mg; 1 g; 2 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxy-PEG10-t-butyl ester is a PEG linker featuring a terminal hydroxyl group and a t-butyl ester-protected carboxyl group. The PEG10 spacer provides enhanced hydrophilicity and solubility in aqueous media. The hydroxyl group offers a versatile site for further derivatization, while the t-butyl ester can be selectively deprotected under acidic conditions.

Molecular Weight

586.7

Molecular Formula

C₂₇H₅₄O₁₃

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid

Purity

98%

Solubility

Water, DMSO, DMF, DCM

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG10-t-butyl ester is used in bioconjugation, drug delivery, and organic synthesis. The terminal hydroxyl group allows for various functional modifications, and the acid-labile t-butyl ester enables controlled release of the carboxylic acid, making it ideal for creating hydrophilic and functionalized biomolecule conjugates in pharmaceutical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.