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Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG12-t-butyl ester, Purity 98%
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Cat. No.: X24-03-YW0646

Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG12-t-butyl ester, Purity 98%

Synonym: 1186025-29-5; Hydroxy-PEG24-t-butyl ester; Ho-peg(24)-co-tbu; Hydroxy-PEG24-Boc; HO-PEG24-CH2CH2COOtBu

  • CAS Number: 1186025-29-5
  • PubChem CID: 51341047
Size
500 mg; 1 g; 2 g
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Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Hydroxy-PEG12-t-butyl ester is a PEG-based linker featuring a terminal hydroxyl group and a t-butyl ester-protected carboxyl group. The hydroxyl group serves as a reactive site for chemical modification, while the t-butyl ester provides protection to the carboxylic acid, enabling controlled deprotection under acidic conditions. The PEG12 spacer enhances hydrophilicity and solubility in aqueous media, making it suitable for diverse applications.
Molecular Weight
674.8
Molecular Formula
C31H62O15
Functional Group 1
Hydroxyl
Functional Group 2
t-Butyl ester
Reactive Group 1
Acid
Reactive Group 2
Nucleophile
Form
Liquid
Purity
98%
Solubility
Water, DMSO, DMF, DCM
Identity
Confirmed by NMR.
Applications
Hydroxy-PEG12-t-butyl ester is widely used in drug delivery, bioconjugation, and polymer synthesis. Its hydroxyl group supports functionalization for advanced material development, and the acid-labile t-butyl ester ensures precise carboxyl group activation. This compound is ideal for creating hydrophilic linkers, stabilizing biomolecules, and designing innovative materials in pharmaceutical and biomedical research.
Storage
Store at -20°C.
For Research Use Only. Not For Clinical Use.
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