Description
Hydroxy-PEG16-t-butyl ester is a PEG linker with a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG16 chain enhances hydrophilicity and solubility in aqueous environments. The hydroxyl group serves as a versatile site for chemical modifications, while the t-butyl ester provides acid-labile protection for controlled carboxylic acid activation.
Applications
Hydroxy-PEG16-t-butyl ester is utilized in drug delivery, bioconjugation, and material synthesis. Its hydroxyl group supports versatile functionalization, and the t-butyl ester allows precise activation of the carboxyl group under acidic conditions, making it ideal for creating hydrophilic linkers and advanced functional materials in pharmaceutical research.