Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG16-t-butyl ester, Purity 98%

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Cat. No.: X24-03-YW0680

Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG16-t-butyl ester, Purity 98%

Synonym: 2592433-80-0; Hydroxy-PEG16-t-butyl ester; Hydroxy-PEG16-Boc; HO-PEG16-CH₂CH₂COOtBu

CAS Number: 2592433-80-0
PubChem CID: 77078319

Size

100 mg; 250 mg; 500 mg

Price

Datasheet

MSDS

Properties

Description

Hydroxy-PEG16-t-butyl ester is a PEG linker with a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG16 chain enhances hydrophilicity and solubility in aqueous environments. The hydroxyl group serves as a versatile site for chemical modifications, while the t-butyl ester provides acid-labile protection for controlled carboxylic acid activation.

Molecular Weight

851.0

Molecular Formula

C₃₉H₇₈O₁₉

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Sticky liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG16-t-butyl ester is utilized in drug delivery, bioconjugation, and material synthesis. Its hydroxyl group supports versatile functionalization, and the t-butyl ester allows precise activation of the carboxyl group under acidic conditions, making it ideal for creating hydrophilic linkers and advanced functional materials in pharmaceutical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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