Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG20-t-butyl ester, Purity 98%

Synonym: Hydroxy-PEG20-Boc; Hydroxy-PEG20-t-butyl ester; Hydroxy-PEG20-tert-butyl ester; MFCD21363265; AKOS040743386

MDL: MFCD21363265
PubChem CID: 77078310

Size

100 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxy-PEG20-t-butyl ester is a PEG linker featuring a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG20 chain enhances hydrophilicity and solubility in aqueous media. The hydroxyl group provides a versatile site for chemical derivatization, while the t-butyl ester offers acid-labile protection for controlled carboxyl activation.

Molecular Weight

1,027.3

Molecular Formula

C₄₇H₉₄O₂₃

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG20-t-butyl ester is widely used in drug delivery, bioconjugation, and polymer synthesis. Its hydroxyl group supports versatile functionalization, and the t-butyl ester allows precise carboxyl activation under acidic conditions, making it ideal for developing hydrophilic linkers and functional biomaterials in pharmaceutical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.