Cat. No.: X24-03-YW0678
Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG20-t-butyl ester, Purity 98%
Synonym: Hydroxy-PEG20-Boc; Hydroxy-PEG20-t-butyl ester; Hydroxy-PEG20-tert-butyl ester; MFCD21363265; AKOS040743386
- MDL: MFCD21363265
- PubChem CID: 77078310
Properties
Description
Hydroxy-PEG20-t-butyl ester is a PEG linker featuring a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG20 chain enhances hydrophilicity and solubility in aqueous media. The hydroxyl group provides a versatile site for chemical derivatization, while the t-butyl ester offers acid-labile protection for controlled carboxyl activation.
Molecular Formula
C47H94O23
Functional Group 1
Hydroxyl
Functional Group 2
t-Butyl ester
Reactive Group 2
Nucleophile
Identity
Confirmed by NMR.
Applications
Hydroxy-PEG20-t-butyl ester is widely used in drug delivery, bioconjugation, and polymer synthesis. Its hydroxyl group supports versatile functionalization, and the t-butyl ester allows precise carboxyl activation under acidic conditions, making it ideal for developing hydrophilic linkers and functional biomaterials in pharmaceutical research.
For Research Use Only. Not For
Clinical Use.