Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG24-t-butyl ester, Purity 97%

Synonym: 1186025-29-5; Hydroxy-PEG24-t-butyl ester; Ho-peg(24)-co-tbu; Hydroxy-PEG24-Boc; HO-PEG24-CH₂CH₂COOtBu

CAS Number: 1186025-29-5

PubChem CID: 51341047

Size

100 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxy-PEG24-t-butyl ester is a PEG linker featuring a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG24 chain enhances hydrophilicity and solubility in aqueous environments. The hydroxyl group supports versatile chemical modifications, while the t-butyl ester offers acid-labile protection for controlled activation of the carboxylic acid.

Molecular Weight

1,203.5

Molecular Formula

C₅₅H₁₁₀O₂₇

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid/Solid (low melting point)

Purity

97%

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG24-t-butyl ester is used in drug delivery, bioconjugation, and material synthesis. Its hydroxyl group enables further functionalization, and the t-butyl ester allows precise activation of the carboxyl group under acidic conditions, making it ideal for creating hydrophilic linkers and functional biomaterials in pharmaceutical and biomedical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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