Cat. No.: X24-03-YW0700
Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG4-t-butyl ester, Purity 98%
Synonym: 518044-32-1; Tert-BUTYL 1-HYDROXY-3,6,9,12-TETRAOXAPENTADECAN-15-OATE; Hydroxy-PEG4-t-butyl ester; Hydroxy-PEG4-t-butly ester; HO-PEG4-CH2CH2COOtBu
- MDL: MFCD11041117
- CAS Number: 518044-32-1
- PubChem CID: 11174684
Properties
Description
Hydroxy-PEG4-t-butyl ester is a PEG linker featuring a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG4 spacer enhances hydrophilicity and solubility in aqueous environments. The hydroxyl group serves as a versatile site for further derivatization, while the t-butyl ester provides acid-labile protection for controlled carboxylic acid activation.
Molecular Formula
C15H30O7
Functional Group 1
Hydroxyl
Functional Group 2
t-Butyl ester
Reactive Group 2
Nucleophile
Identity
Confirmed by NMR.
Applications
Hydroxy-PEG4-t-butyl ester is widely used in bioconjugation, drug delivery, and polymer synthesis. Its hydroxyl group supports versatile functionalization, and the t-butyl ester allows precise activation of the carboxyl group under acidic conditions, making it ideal for creating hydrophilic linkers and functional materials in pharmaceutical and biomedical research.
For Research Use Only. Not For
Clinical Use.