Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG5-t-butyl ester, Purity 98%

Synonym: 850090-09-4; Hydroxy-PEG5-t-butyl ester; HO-PEG5-tBu; HO-PEG5-CH₂CH₂COOtBu

CAS Number: 850090-09-4
PubChem CID: 53486144

Size

500 mg; 1 g; 5 g; 10 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxy-PEG5-t-butyl ester is a PEG linker featuring a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG5 spacer enhances water solubility and hydrophilicity in aqueous environments. The hydroxyl group provides versatility for chemical modifications, while the t-butyl ester offers acid-labile protection for controlled carboxylic acid activation.

Molecular Weight

366.5

Molecular Formula

C₁₇H₃₄O₈

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG5-t-butyl ester is widely used in bioconjugation, drug delivery, and polymer synthesis. The hydroxyl group supports functionalization, and the t-butyl ester enables precise activation of the carboxyl group under acidic conditions, making it ideal for creating hydrophilic linkers and functionalized materials in biomedical and pharmaceutical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.