Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG6-t-butyl ester, Purity 98%

Synonym: 361189-64-2; Hydroxy-PEG6-t-butyl ester; Hydroxy-PEG6-Boc; PEG7-t-butly ester

MDL: MFCD13185017
CAS Number: 361189-64-2
PubChem CID: 51341046

Size

250 mg; 500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxy-PEG6-t-butyl ester is a PEG linker featuring a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG6 chain enhances hydrophilicity and solubility in aqueous environments. The hydroxyl group allows for versatile chemical modifications, while the t-butyl ester provides acid-labile protection for controlled carboxylic acid activation.

Molecular Weight

410.5

Molecular Formula

C₁₉H₃₈O₉

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Colorless liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG6-t-butyl ester is widely used in drug delivery, bioconjugation, and polymer synthesis. Its hydroxyl group supports further functionalization, and the t-butyl ester allows precise activation of the carboxyl group under acidic conditions, making it ideal for creating hydrophilic linkers and advanced materials in biomedical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.