Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG8-t-butyl ester, Purity 97%

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Cat. No.: X24-03-YW0645

Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG8-t-butyl ester, Purity 97%

Synonym: 1334177-84-2; Hydroxy-PEG8-t-butyl ester; HO-PEG8-CH₂CH₂COOtBu; Hydroxy-PEG8-Boc; t-Butyl 3-Hydroxy(peg8)propionate

MDL: MFCD11041105
CAS Number: 1334177-84-2
PubChem CID: 51340944

Size

500 mg; 1 g; 5 g

Price

Datasheet

MSDS

Properties

Description

Hydroxy-PEG8-t-butyl ester is a functionalized PEG linker comprising a terminal hydroxyl group and a t-butyl ester-protected carboxyl group. The hydroxyl group provides a reactive site for chemical modifications, while the t-butyl ester ensures stability and controlled deprotection under acidic conditions. The PEG8 chain enhances solubility in aqueous environments, making it highly hydrophilic and versatile for various applications.

Molecular Weight

498.6

Molecular Formula

C₂₃H₄₆O₁₁

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid

Purity

97%

Solubility

Water, DMSO, DMF, DCM

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG8-t-butyl ester is used in bioconjugation, drug delivery, and advanced material synthesis. The hydroxyl group supports versatile functionalization, and the t-butyl ester allows for targeted release of carboxylic acid. Its hydrophilic PEG spacer facilitates the development of water-soluble linkers and functionalized biomaterials for pharmaceutical and biomedical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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