Hydroxyl/t-Butyl ester PEG reagent, Hydroxy-PEG9-t-butyl ester, Purity 98%

Synonym: 2055042-66-3; Hydroxy-PEG9-Boc; HYDROXY-PEG9-t-ButylESTER; Hydroxy-PEG9-t-butyl ester

CAS Number: 2055042-66-3
PubChem CID: 123132119

Size

500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxy-PEG9-t-butyl ester is a PEG linker featuring a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG9 chain enhances hydrophilicity and solubility in aqueous environments. The hydroxyl group offers a versatile site for chemical modifications, while the t-butyl ester provides acid-labile protection for controlled carboxylic acid activation.

Molecular Weight

542.7

Molecular Formula

C₂₅H₅₀O₁₂

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Sticky liquid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG9-t-butyl ester is widely used in drug delivery, bioconjugation, and polymer synthesis. The hydroxyl group supports further derivatization, and the t-butyl ester enables precise activation of the carboxyl group under acidic conditions, making it ideal for creating hydrophilic linkers and functional materials in biomedical and pharmaceutical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.