Hydroxyl/t-Butyl ester PEG reagent, N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester), Purity 98%

Synonym: 2112734-70-8; N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester); N-(Hydroxy-PEG3)-N-bis(PEG4-Boc); Tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl-[2-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

CAS Number: 2112734-70-8
PubChem CID: 126961968

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) is a branched PEG linker featuring a terminal hydroxyl group and two t-butyl ester-protected carboxyl groups. The hydroxyl group supports versatile chemical modifications, while the t-butyl groups offer acid-labile protection for controlled carboxylic acid activation. The PEG structure enhances solubility and biocompatibility in aqueous environments.

Molecular Weight

802.0

Molecular Formula

C₃₈H₇₅NO₁₆

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) is used in drug delivery, bioconjugation, and advanced material synthesis. The hydroxyl group enables further functionalization, and the t-butyl esters provide precise carboxyl activation under acidic conditions, making it ideal for creating hydrophilic linkers and functionalized biomaterials in biomedical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.