Cat. No.: X24-03-YW0667
Hydroxyl/t-Butyl ester PEG reagent, N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester), Purity 98%
Synonym: 2112734-70-8; N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester); N-(Hydroxy-PEG3)-N-bis(PEG4-Boc); Tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl-[2-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
- CAS Number: 2112734-70-8
- PubChem CID: 126961968
Size
100 mg; 250 mg; 500 mg
Properties
Description
N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) is a branched PEG linker featuring a terminal hydroxyl group and two t-butyl ester-protected carboxyl groups. The hydroxyl group supports versatile chemical modifications, while the t-butyl groups offer acid-labile protection for controlled carboxylic acid activation. The PEG structure enhances solubility and biocompatibility in aqueous environments.
Molecular Formula
C38H75NO16
Functional Group 1
Hydroxyl
Functional Group 2
t-Butyl ester
Reactive Group 2
Nucleophile
Identity
Confirmed by NMR.
Applications
N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) is used in drug delivery, bioconjugation, and advanced material synthesis. The hydroxyl group enables further functionalization, and the t-butyl esters provide precise carboxyl activation under acidic conditions, making it ideal for creating hydrophilic linkers and functionalized biomaterials in biomedical research.
For Research Use Only. Not For
Clinical Use.