Description
N,N-diethanol amine-PEG4-tert-butyl ester is a PEG-based reagent featuring two hydroxyl groups and a t-butyl ester-protected carboxyl group. The hydroxyl groups provide nucleophilic sites for further functionalization, while the t-butyl ester can be selectively deprotected under mild acidic conditions. The PEG4 spacer enhances water solubility and biocompatibility, making it suitable for various chemical and biomedical applications.
Applications
N,N-diethanol amine-PEG4-tert-butyl ester is widely used in drug delivery, bioconjugation, and polymer synthesis. Its dual hydroxyl groups allow for versatile chemical modifications, and the acid-labile t-butyl ester enables controlled release of the carboxylic acid, making it ideal for creating hydrophilic linkers, functionalized biomolecules, and advanced materials in pharmaceutical and biomedical research.