Cat. No.: X24-03-YW0642
Hydroxyl/t-Butyl ester PEG reagent, N,N-diethanol amine-PEG4-tert-butyl ester, Purity 95%
Synonym: 2279944-66-8; N,N-Diethanol amine-PEG4-Boc; N,N-Diethanol amine-PEG4-tert-butyl ester; Tert-butyl 1-hydroxy-3-(2-hydroxyethyl)-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate; AKOS040743708
- CAS Number: 2279944-66-8
- PubChem CID: 137334038
Properties
Description
N,N-diethanol amine-PEG4-tert-butyl ester is a PEG-based reagent featuring two hydroxyl groups and a t-butyl ester-protected carboxyl group. The hydroxyl groups provide nucleophilic sites for further functionalization, while the t-butyl ester can be selectively deprotected under mild acidic conditions. The PEG4 spacer enhances water solubility and biocompatibility, making it suitable for various chemical and biomedical applications.
Molecular Formula
C19H39NO8
Functional Group 1
Hydroxyl
Functional Group 2
t-Butyl ester
Reactive Group 2
Nucleophile
Identity
Confirmed by NMR.
Applications
N,N-diethanol amine-PEG4-tert-butyl ester is widely used in drug delivery, bioconjugation, and polymer synthesis. Its dual hydroxyl groups allow for versatile chemical modifications, and the acid-labile t-butyl ester enables controlled release of the carboxylic acid, making it ideal for creating hydrophilic linkers, functionalized biomolecules, and advanced materials in pharmaceutical and biomedical research.
For Research Use Only. Not For
Clinical Use.