Cat. No.: X24-03-YW0618
Hydroxyl/t-Butyl ester PEG reagent, t-Butyl-ester-PEG4-(CH2)3OH, Purity 98%
Synonym: t-Boc-O-PEG4-(CH2)3OH; t-BuO-PEG4-(CH2)3OH
Properties
Description
t-Butyl-ester-PEG4-(CH2)3OH is a bifunctional PEG linker featuring a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG4 spacer enhances hydrophilicity and solubility in aqueous media, while the t-butyl ester provides stability during synthesis and can be selectively removed under acidic conditions.
Molecular Formula
C16H32O7
Functional Group 1
Hydroxyl
Functional Group 2
t-Butyl ester
Reactive Group 2
Nucleophile
Identity
Confirmed by NMR.
Applications
t-Butyl-ester-PEG4-(CH2)3OH is used in drug delivery, surface modification, and bioconjugation. The terminal hydroxyl allows for further derivatization, and the t-butyl ester deprotection enables site-specific conjugation to form esters or amides in targeted synthesis applications.
For Research Use Only. Not For
Clinical Use.